This product is a proprietary blend consisting of N-Ethly Hexedrone aka N-E-H, designed to make the research of this compound easier in the lab, making it more akin to other compounds that require a license to study.Hexecaine,n-ethylhexedrone buy,nep drug,n-ethyl-hexedrone review,3-mmc
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N-ethylhexedrone is a molecule of the cathinone chemical class. The term “substituted cathinone” refers to a broad array of substances based on cathinone, the principally active constituent of the khat plant.
Cathinone is principally constituted of a amphetamine core (a phenethylamine core with an alkyl group attached to the alpha carbon) and an oxygen group attached to the beta carbon. Cathinones are also known as the beta-ketone (βk) (double-bonded oxygen to the β-carbon) analogs of amphetamines.
Notably, the cathinone backbone can be modified in three different places to create hundreds of possible compounds, which include substituents such as on the aromatic ring, the alpha carbon, or the amine group.
Very little data exists on the human pharmacokinetics and pharmacodynamics of N-ethylhexedrone and other substituted cathinones.
Like amphetamines, synthetic cathinones exert their stimulating and sympathomimetic effects via increasing synaptic concentration of catecholamines such as dopamine, serotonin and norepinephrine.
These molecules are able to inhibit monoamine reuptake transporters producing a decreased clearance of the neurotransmitters from the synapse. Furthermore, they may cause release of biogenic amines from intracellular stores.Hexecaine, n-ethylhexedrone buy, nep drug, n-ethyl-hexedrone review, 3-mmc
Synthetic cathinones are generally less able than amphetamines to cross the blood–brain barrier because the beta-keto group causes an increase in polarity.mdmai
Unlike other synthetic cathinones, pyrrolidine derivatives have a higher ability to cross the blood–brain barrier because the pyrrolidine ring confers a low polarity to these molecules.
The studies on the metabolism of synthetic cathinones have shown that they are N-demethylated, the keto group is reduced to hydroxyl and ring alkyl groups are oxidised.